Searchable abstracts of presentations at key conferences in endocrinology

ea0056p581 | Obesity | ECE2018

Plasma metabolomic markers of insulin resistance in humans.

Pivovarova Olga , Gahwiler Roman , Nikiforova Viktoria , von Loffelholz Christian , Lisec Jan , Erban Alexander , Zerkiebel Nic , Willmitzer Lothar , Pfeiffer Andreas F H , Weickert Martin O , Rudovich Natalia N

Introduction: Insulin resistance (IR), a pathological state of low sensitivity to insulin in humans and animlas, is closely associated with type 2 diabetes mellitus, obesity and cardiovasculare dieseas. IR can be quantified using detailed protocols, such as the euglycemic-hyperinsulinemic clamp (EC) technique and the intravenous glucose tolerance test, or based on indices derived from the oral glucose tolerance test. Although these indices showed greater association with the i...